Substance specific to human PD-1
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United States of America Patent
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Oct 10, 2017
Grant Date -
Apr 30, 2015
app pub date -
Dec 29, 2014
filing date -
Jan 23, 2003
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Abstract
The present invention relates to a substance specific to human PD-1 comprising a part that recognizes human PD-1, a part that recognizes a membrane protein in cell membrane of human PD-1-expressing cells, and linkers. Since the substance specific to human PD-1 selectively can recognize human PD-1 and a membrane protein on cell membrane of human PD-1-expressing cells and can transmit inhibitory signal of human PD-1, it is useful for therapy and/or prevention of diseases caused by immunopathy.
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