Water soluble 4-azapodophyllotoxin analogs

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United States of America Patent

PATENT NO 9783547
SERIAL NO

15111711

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Abstract

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The present invention relates to 4-azapodophyllotoxin analogs of formula (I) in which X, R1, R2, R3, R4 and Ar are as defined in claim 1, preferably a pharmaceutically acceptable salt thereof, optionally in the form of a solvate, a composition comprising said analogs, their use as medicament, in particular for the treatment of cancer, and a process for their preparation.

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UNIVERSITÉ PARIS CITÉ85 BOULEVARD SAINT-GERMAIN PARIS 75006

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chabot, Guy Charenton le Pont, FR 2 9
Desbene-Finck, Stéphanie Paris, FR 1 0
Giorgi-Renault, Sylviane Paris, FR 3 8
Helissey, Philippe Villeparisis, FR 1 0
Labruere, Raphaël Orsay, FR 1 0
Scherman, Daniel Paris, FR 50 543
Testud, Marlène Paris, FR 1 0

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