Composite magnetic nanoparticle drug delivery system

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United States of America Patent

PATENT NO 9782342
APP PUB NO 20120265001A1
SERIAL NO

13271172

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Abstract

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A composite magnetic nanoparticle drug delivery system provides targeted controlled release chemotherapies for cancerous tumors and inflammatory diseases. The magnetic nanoparticle includes a biocompatible and biodegradable polymer, a magnetic nanoparticle, the biological targeting agent human serum albumin, and a therapeutic pharmaceutical composition. The composite nanoparticles are prepared by oil-in-oil emulsion/solvent evaporation and high shear mixing. An externally applied magnetic field draws the magnetic nanoparticles to affected areas. The biological targeting agent draws the nanoparticles into the affected tissues. Polymer degradation provides controlled time release delivery of the pharmaceutical agent.

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Patent Owner(s)

Patent OwnerAddress
WICHITA STATE UNIVERSITYWICHITA KS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Asmatulu, Ramazan Wichita, US 7 54
Misak, Heath Wichita, US 3 16
Wooley, Paul Wichita, US 1 16
Yang, Shang-You Wichita, US 1 16

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