Engineered antibody for inhibition of fibrosis
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
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Oct 3, 2017
Issued Date -
N/A
app pub date -
Feb 26, 2013
filing date -
Apr 20, 2012
priority date (Note) -
In Force
status (Latency Note)
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Abstract
A chimeric, humanized or single-chain antibody contains a light chain variable region containing the complementarity determining regions of SEQ ID NO: 1, SEQ ID NO:2 and SEQ ID NO:3, and a heavy chain variable region containing the complementarity determining regions SEQ ID NO:4, SEQ ID NO:5 and SEQ ID NO:6. The antibody or antibody fragment thereof is capable of binding the C-terminal telopeptide of the α2(I) chain of human collagen I, and is useful in the treatment of diseases or disorders associated with excessive collagen fibril.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
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THOMAS JEFFERSON UNIVERSITY | 925 CHESTNUT STREET SUITE 110 PHILADELPHIA PA 19107 |
International Classification(s)
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
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Fertala, Andrzej | Voorhees, US | 12 | 82 |
# of filed Patents : 12 Total Citations : 82 | |||
Steplewski, Andrzej | Phoenixville, US | 5 | 4 |
# of filed Patents : 5 Total Citations : 4 |
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Patent Citation Ranking
- 2 Citation Count
- A61K Class
- 45.09 % this patent is cited more than
- 8 Age
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