R-spondin variants, compositions, and methods of use

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United States of America Patent

PATENT NO 9777052
APP PUB NO 20160152947A1
SERIAL NO

14956921

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Abstract

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R-spondin variants comprising a ZNRF3 binding region of a first R-spondin and an LGR4 binding region of a second R-spondin are disclosed. Cell culture media and compositions containing the R-spondin variants, as well as methods of their use, are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA660 PARRINGTON OVAL ROOM 119 NORMAN OK 73019

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Pioszak, Augen A Edmond, US 4 17

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