Methods and compositions for inducing an immune response to EGFRvIII
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United States of America Patent
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Oct 3, 2017
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Nov 25, 2015
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Nov 17, 2010
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Abstract
The present invention relates to methods of inducing a T-cell response against a EGFRvIII in a subject. These method comprise administering to a subject a composition which expresses at least one immunogenic polypeptide, the amino acid sequence of which comprise a plurality of EGFRvIII polypeptide sequences, the sequence of which each comprise EEKKGNYV (SEQ ID NO: 3), and/or administering the polypeptide itself.
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