Klotho variant polypeptides

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United States of America Patent

PATENT NO 9771567
SERIAL NO

14394465

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Abstract

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Disclosed are Klotho variant proteins in which residue Glu414 and/or residue Asp238 is substituted with an amino acid different than L-Glu or L-Asp, respectively, as well as polynucleotides encoding the variant proteins, and the use thereof in therapy, especially for the treatment of cancers, especially breast cancer and pancreatic cancer.

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Patent Owner(s)

Patent OwnerAddress
TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTDRAMAT GAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Rubinek, Tamar Or Yehuda, IL 6 66
Wolf, Ido Or Yehuda, IL 9 90

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