Tissue repair scaffold
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United States of America Patent
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Sep 26, 2017
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app pub date -
Jun 13, 2011
filing date -
Dec 12, 2008
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Abstract
The present invention provides a tissue repair scaffold comprising a secondary fiber bundle, the secondary fiber bundle comprising a plurality of primary fiber bundles, each primary fiber bundle comprising a plurality of fibers, wherein the fibers comprise a biocompatible polymer. In embodiments the biocompatible polymer is polycaprolactone (PCL) (also known as poly-ε-caprolactone) and the average diameter of the fibers is less than 1 μm. The scaffold is particularly adapted for tendon repair. In vivo mouse studies demonstrate that tendon repair can be achieved with normal ambulation returning after 24-48 hours. The scaffolds were easy to handle during surgery, being non-slippery and easy to suture in place.
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