Self-assembling amphiphilic polymers as anti-cancer agents
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United States of America Patent
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Sep 26, 2017
Grant Date -
Sep 23, 2010
app pub date -
Jul 19, 2007
filing date -
Jul 19, 2007
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Abstract
The invention provides amphiphilic biocompatible copolymers which have a hydrophilic backbone and pendant hydrophobic groups. The polymers form nanoscale molecular aggregates in aqueous environments, which have hydrophobic interiors within which anticancer drugs may be solubilized. The polymers optionally feature attached antibodies, receptor ligands, and other targeting moieties which mediate adherence of the drug-carrying aggregates to targeted cancer cells.
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