Electrospray ionizer for mass spectrometry of aerosol particles

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United States of America Patent

PATENT NO 9768005
SERIAL NO

15135132

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Abstract

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A device and method are disclosed to apply ESI-based mass spectroscopy to submicrometer and nanometer scale aerosol particles. Unipolar ionization is utilized to charge the particles in order to collect them electrostatically on the tip of a tungsten rod. Subsequently, the species composing the collected particles are dissolved by making a liquid flow over the tungsten rod. This liquid with dissolved aerosol contents is formed into highly charged droplets, which release unfragmented ions for mass spectroscopy, such as time-of-flight mass spectroscopy. The device is configured to operate in a switching mode, wherein aerosol deposition occurs while solvent delivery is turned off and vice versa.

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Patent Owner(s)

Patent OwnerAddress
REGENTS OF THE UNIVERSITY OF MINNESOTA200 OAK STREET NORTHEAST 600 MCNAMARA ALUMNI CENTER MINNEAPOLIS MN 55455-2020

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
He, Siqin Qianjiang, CN 3 2
Hogan, Chris Minneapolis, US 2 6
Li, Lin Arden Hills, US 440 2643
Liu, Benjamin Y H North Oaks, US 65 1792
Naqwi, Amir Eden Prairie, US 2 37
Romay, Francisco Vadnais Heights, US 2 6

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