Reduction of migration shift assay interference
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United States of America Patent
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Sep 19, 2017
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app pub date -
Apr 8, 2004
filing date -
Apr 14, 2003
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Abstract
This invention provides methods and compositions, e.g., to reduce interference from non-specific binding sample constituents in a migration shift assay. Interference due to non-specific binding of sample constituents to an affinity substance (e.g., an affinity molecule or a conjugate of an affinity molecule and a charged carrier molecule) is prevented by, e.g., binding the constituents to charged polymers such as heparin sulfate.
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