Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion
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United States of America Patent
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Sep 19, 2017
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May 12, 2016
app pub date -
Jan 8, 2016
filing date -
Sep 7, 2010
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Abstract
The invention relates to recombinant host cells having at least one integrated polynucleotide encoding a polypeptide that catalyzes a step in a pyruvate-utilizing biosynthetic pathway, e.g., pyruvate to acetolactate conversion. The invention also relates to methods of increasing the biosynthetic production of isobutanol, 2,3-butanediol, 2-butanol or 2-butanone using such host cells.
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