TEM8 antibodies and their use in treatment and detection of tumors

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United States of America Patent

PATENT NO 9765142
SERIAL NO

15028337

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Abstract

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Antibodies that specifically bind TEM8 protein, conjugates thereof, and their use, are disclosed herein. In some examples the conjugates and antibodies are useful for methods of detecting and treating pathogenic angiogenesis. In other examples the conjugates and antibodies are useful for methods of detecting and treating cancer. In additional examples, the conjugates and antibodies are useful for methods of decreasing binding of Anthrax protective antigen to a cell.

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Patent Owner(s)

Patent OwnerAddress
THE UNITED STAES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES6011 EXECUTIVE BOULEVARD SUITE 325 MSC 7660 BETHESDA MD 20892-7660

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Decrescenzo, Gary Parkville, US 28 33
Dimitrov, Dimiter Frederick, US 20 63
Saha, Saurabh Wellesley Hills, US 51 217
St, Croix Brad Frederick, US 25 141
Welsch, Dean Parkville, US 28 51
Zhang, Xiaoyan Michelle Lexington, US 11 46
Zhu, Zhongyu Frederick, US 64 134
Zudaire, Enrique Germantown, US 17 46

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