Allosteric hemoglobin modifiers with nitric oxide releasing moiety

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United States of America Patent

PATENT NO 9765017
SERIAL NO

15107962

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Abstract

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Allosteric hemoglobin (Hb) modifiers of hemoglobin which contain nitric oxide (NO) moieties allowing for the release of NO in vivo. The compounds retain the oxygen delivery capability of the allosteric hemoglobin modifier to bind Hb and enhance Hb's ability to deliver oxygen to cells and tissues, and also release NO from the NO moiety. Methods of delivering oxygen and/or NO to cells and tissues are also provided.

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Patent Owner(s)

Patent OwnerAddress
VIRGINIA COMMONWEALTH UNIVERSITY800 EAST LEIGH STREET SUITE 3000 RICHMOND VA 23298

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Danso-Danquah, Richmond Richmond, US 10 101
Ghatge, Mohini Richmond, US 5 5
Mangino, Martin Richmond, US 4 11
Safo, Martin K Richmond, US 25 73
Venitz, Jurgen Richmond, US 7 2
Ward, Kevin R Richmond, US 65 1721

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