Dosing regimens of celgosivir for the treatment of dengue

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United States of America Patent

PATENT NO 9763921
APP PUB NO 20160030403A1
SERIAL NO

14772873

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Abstract

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Methods of treating a dengue virus (DENV) infection in a human subject, comprising administering to the human subject a compound of Formula (I), or pharmaceutical composition comprising a compound of Formula (I): A compound of Formula (I) can be administered within onset of fever to 72 hours of fever onset due to dengue infection and then every 6 to 12 hours until there is an improvement in the infection or between from about 1 day to about 10 days. The methods of the invention can be used to treat primary and secondary DENV1-4 viral infections.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL UNIVERSITY OF SINGAPORE21 LOWER KENT RIDGE ROAD SINGAPORE 119077
SINGAPORE HEALTH SERVICES PTE LTD31 THIRD HOSPITAL AVENUE #03-03 BOWYER BLOCK C SINGAPORE 168753
60 DEGREES PHARMACEUTICALS LLC1025 CONNECTICUT AVENUE N W WASHINGTON DC 20036

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dow, Geoffrey S Washington, US 15 8
Low, Jenny Singapore, SG 4 7
Morrish, Glynn Toowong, AU 3 7
Ooi, Eng Eong Singapore, SG 13 60
Rathore, Abhay Singapore, SG 4 7
Reid, Mark Toowong, AU 8 77
Sung, Cynthia Singapore, SG 11 496
Vasudevan, Subhash Singapore, SG 5 56
Watanabe, Satoru Singapore, SG 270 2860

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