Sortase-modified VHH domains and uses thereof

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United States of America Patent

PATENT NO 9751945
SERIAL NO

14394046

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Abstract

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In some aspects, polypeptides comprising single domain antibodies and methods of identifying single domain antibodies are provided. In some embodiments polypeptides comprising a single domain antibody and a sortase recognition sequence, are provided. In some aspects, products and methods of use in modulating the immune system, e.g., modulating an immune response, are provided.

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Patent Owner(s)

Patent OwnerAddress
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH455 MAIN STREET CAMBRIDGE MA 02142-1479

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cragnolini, Juanjo Cambridge, US 1 43
Ploegh, Hidde Brookline, US 6 70
Popp, Maximilian Pittsford, US 1 43

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