Arbekacin derivative, and production and use thereof
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United States of America Patent
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Sep 5, 2017
Grant Date -
Apr 7, 2016
app pub date -
May 29, 2014
filing date -
May 30, 2013
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Abstract
It has been found that adding carbon dioxide or the like to a solution containing arbekacin free base makes it possible to produce arbekacin derivatives including arbekacin carbonate and carbamic acid of arbekacin. Moreover, it has been found that the arbekacin derivatives have a high stability, and that the use thereof enables efficient productions of highly-pure arbekacin free base and pharmaceutically acceptable salt thereof.
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