Crystalline form I of ibrutinib

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United States of America Patent

PATENT NO 9751889
SERIAL NO

15100247

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Abstract

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Crystalline Form I of ibrutinib, processes for its preparation, pharmaceutical compositions comprising the new Form, and use of Form I of ibrutinib for treating or delaying diseases or disorders related to activity of Bruton's tyrosine kinase (BTK) proteins are disclosed. The novel Form was characterized by X-ray powder diffraction, differential scanning calorimetry, and other techniques. It can be readily prepared and is suitable for use in the preparation of solid dosage forms.

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Patent Owner(s)

Patent OwnerAddress
CRYSTAL PHARMATECH CO LTD218 XINGHU STREET B4-101 BIOBAY SUZHOU INDUSTRIAL PARK SUZHOU JIANGSU 215123
SUZHOU PENGXU PHARMATECH CO LTD3RD FLOOR BUILDING 7 2358 CHANGAN ROAD WUJIANG SUZHOU 215200

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Minhua Scotch Plains, US 84 96
Ge, Heng Suzhou, CN 4 16
Li, Pixu Suzhou, CN 15 22
Lu, Fei Suzhou, CN 145 842
Wang, Peng Forest Hills, US 1420 6748
Yang, Chaohui Suzhou, CN 28 97
Zhang, Xiaoyu Suzhou, CN 147 948
Zhang, Yanfeng Suzhou, CN 177 515

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