Precursor compound connected to solid support for manufacturing 18F radiopharmaceutical, method for manufacturing same, and application thereof
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United States of America Patent
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Sep 5, 2017
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N/A
app pub date -
Dec 13, 2011
filing date -
Dec 14, 2010
priority date (Note) -
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Abstract
The present invention relates to a solid precursor in the form of an organic salt, the solid precursor having a solid support, a method for manufacturing same, and an application thereof. The solid precursor of the present invention enables omission of the [18F]fluoride refining process using additional cartridge, and the use of excessive phase-transfer catalyst, and can easily remove remaining substance after reaction through the solid support inside the precursor. The solid precursor of the present invention is very appropriate for an automated synthesis device as an all-in-one system that can carry out overall process of [18F]fluorosis reaction, when used by charging in a cartridge.
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International Classification(s)
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C07H:SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTI....
- C08F:MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONL....
- C07D:HETEROCYCLIC COMPOUNDS
- C07C:ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07B:GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS TH....
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