RNA duplexes with single stranded phosphorothioate nucleotide regions for additional functionality

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United States of America Patent

PATENT NO 9745574
SERIAL NO

13147882

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Abstract

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The present invention relates to RNAi constructs and their use in gene silencing. RNAi constructs associated with the invention contain a double stranded region connected to a single stranded region of phosphorothioate modified nucleotides.

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Patent Owner(s)

Patent OwnerAddress
PHIO PHARMACEUTICALS CORP257 SIMARANO DRIVE SUITE 101 MARLBOROUGH MA 01752

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kamens, Joanne Newton, US 34 2026
Khvorova, Anastasia Westborough, US 393 10160
Salomon, William Worcester, US 31 1852
Woolf, Tod M Sudbury, US 60 3269

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