Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors

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United States of America Patent

PATENT NO 9745295
SERIAL NO

14786464

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Abstract

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The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4, and R4 are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).

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Patent Owner(s)

Patent OwnerAddress
MERCK SHARP & DOHME LLC126 EAST LINCOLN AVENUE RAHWAY NJ 07065

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Altman, Michael D Needham, US 65 795
Andresen, Brian M Sharon, US 20 235
Anthony, Neville J Northborough, US 63 1842
Childers, Kaleen K Newton, US 1 7
Deng, Qiaolin Edison, US 31 115
Donofrio, Anthony Cambridge, US 23 225
DuBois, Byron New York, US 3 14
Ellis, John Michael Needham, US 23 252
Grimm, Jonathan Ashburn, US 13 156
Guay, Daniel Lachine, CA 52 1498
Lebrun, Marie-Eve Dollard-des-Ormeaux, CA 3 16
Liu, Yuan Belmont, US 306 2821
Machacek, Michelle R Brookline, US 22 299
Miller, Thomas A Wakefield, US 83 1391
Northrup, Alan B Reading, US 41 468
Robichaud, Joel S Dollard-des-Ormeaux, CA 6 68
Romeo, Eric T Allston, US 6 58
Spencer, Kerrie B Woonsocket, US 6 107
Wang, Liping Dayton, US 148 523
Woo, Hyun Chong Natick, US 10 54

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