Compound or pharmaceutically acceptable salt thereof, and pharmaceutical composition containing same as active ingredient

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9745280
APP PUB NO 20160340331A1
SERIAL NO

15216838

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Abstract

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A compound inhibiting Hsp90 and a pharmaceutical composition including the same as an active ingredient are described, which compound is represented by formula 2 and suppresses the expression of Hsp90, inhibits the accumulation of HIF-1α, the Hsp90 client protein, and efficiently inhibits the activation of VEGF. The compound displays low cytotoxicity and can be effectively used as an active ingredient of an anti-cancer agent, a diabetic retinopathy treating agent, and an anti-arthritic agent.

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Patent Owner(s)

Patent OwnerAddress
SNU R&DB FOUNDATION1 GWANAK-RO GWANAK-GU SEOUL 08826

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
An, Hongchan Seoul, KR 3 0
Kim, Jeong Hun Seoul, KR 139 1364
Kim, Kyu-Won Seoul, KR 14 49
Kim, Sang Geon Seoul, KR 12 37
Lee, Ho-Young Seoul, KR 131 1578
Lee, Seungbeom Seoul, KR 5 9
Suh, Young-Ger Seoul, KR 12 27

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