Group of STAT3 pathway inhibitors and cancer stem cell pathway inhibitors
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United States of America Patent
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Aug 29, 2017
Grant Date -
Oct 4, 2012
app pub date -
Sep 10, 2008
filing date -
Sep 10, 2007
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Abstract
The present invention relates to the use of a novel class of cancer stem cell pathway (CSCP) inhibitors; to methods of using such compounds to treat refractory, recurrent, or metastatic cancers; to methods of selective killing cancer cells by using such compounds with specific administration regimen; to methods of targeting cancer stem cells by inhibiting Stat3 pathway; to methods of using novel compounds in the treatment of conditions or disorders in a mammal related to aberrant Stat3 pathway activity; and to processes for preparing such compounds and intermediates thereof, and to the pharmaceutical composition of relevant compounds, and to the specific methods of administration of these compounds.
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