Functionalized liposomes useful for the delivery of bioactive compounds

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United States of America Patent

PATENT NO 9744247
SERIAL NO

14411097

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Abstract

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The invention relates to conjugates in which a sterol is functionalized by an ether bond with a water-soluble polymer to which a guiding ligand is bound. These conjugates improve the physico-chemical and delivery properties of their carrying vesicles, making these more stable, homogeneous and effective. A method for their preparation, a pharmaceutical composition containing said liposomes, and their therapeutic use are described as well.

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Patent Owner(s)

Patent OwnerAddress
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)C/ SERRANO 117 28006 MADRID SPAIN
UNIVERSITAT DE BARCELONACENTRO DE PATENTES UB BALDIRI REIXAC 4 TORRE D BARCELONA 08028
UNIVERSITAT AUTONOMA DE BARCELONAPLAÇA CIVICA UAB CAMPUS BARCELONA 08193
FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA08035 BARCELONA
FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)BALDIRI REIXAC 10-12 BARCELONA 08028
FUNDACIÓ PARC CIENTÍFIC DE BARCELONAC BALDIRI I REIXAC 10-12 BARCELONA E-08028
CENTRO DE INVESTIGACIÓN BIOMÉDICA EN REDINSTITUTO DE SALUD CARLOS III PABELLÓN 11 PLANTA BAJA C MONFORTE DE LEMOS 3-5 MADRID 28029

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abasolo, Olaortua Ibane Barcelona, ES 2 4
Albericio, Palomera Fernando Barcelona, ES 12 27
Cabrera, Puig Ingrid Sabadell, ES 3 5
Corchero, Nieto Jose Luis Granollers, ES 3 4
Elizondo, Saez De Vicuña Elisa Barcelona, ES 1 4
Melgarejo, Diaz Marta Badalona, ES 1 4
Pulido, Martinez Daniel Viladecans, ES 2 4
Royo, Expósito Miriam Barcelona, ES 2 4
Sala, Vergés Santiago Vic, ES 3 4
Schwartz, Navarro Simón Cardedeu, ES 5 4
Veciana, Miró Jaume Barcelona, ES 7 5
Ventosa, Rull Leonor Barcelona, ES 4 5
Villaverde, Corrales Antonio Pedro El Masnou, ES 9 13

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