Anti-phospho-Akt antibodies
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United States of America Patent
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Aug 22, 2017
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app pub date -
Apr 13, 2015
filing date -
May 29, 2008
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Abstract
The Present invention relates to antibodies that immunospecifically bind to phospho-Akt and certain p-Akt substrates. The invention encompasses human and humanized forms of the antibodies and their use in treating cancers and other proliferative disorders. The invention also relates to p-Akt derived peptides useful for preparing the antibodies. Methods and compositions for detecting, diagnosing, treating or ameliorating a disease or disorder, especially cancer and other proliferative disorders using the present antibodies also are disclosed.
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