Methods and systems of detecting exocytosis of a target molecule from a population of cells
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United States of America Patent
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Aug 22, 2017
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Mar 24, 2016
app pub date -
May 12, 2014
filing date -
May 13, 2013
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Abstract
A method of detecting exocytosis of a target molecule from a population of cells derived from a human subject, includes applying first and second electrical signals, each having a respective frequency, across the population of cells. Each of the first and second electrical signals being either an alternating current or an alternating voltage. The method includes measuring a first voltage change if the first electrical signal is an alternating current or measuring a first current change if the first electrical signal is an alternating voltage, and measuring a second voltage change if the second electrical signal is an alternating current or measuring a second current change if the second electrical signal is an alternating voltage. The method includes determining an electrical impedance of the population of cells, a change in that impedance indicating an amount of the target molecule released from the population of cells.
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