Method of DNA sequencing by polymerisation

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United States of America Patent

PATENT NO 9738928
SERIAL NO

15334593

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Abstract

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The present invention relates to a method for the determination of a nucleic acid sequence by physical manipulation. The method is based on the precise determination of the localization of the replicating fork on the template by measuring the physical distance between one end of the molecule and the fork. This allows the determination of the physical location of the site where a pause or a blockage of the replication occurs, and deducing therefrom information on the sequence of the nucleic acid.

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Patent Owner(s)

Patent OwnerAddress
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)3 RUE MICHEL ANGE PARIS 75016

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allemand, Jean-Francois Arcueil, FR 5 18
Bensimon, David Paris, FR 29 377
Croquette, Vincent Antony, FR 16 81
Ding, Fang-Yuan Paris, FR 6 29
Manosas, Maria Barcelona, ES 5 11

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