Therapeutically active compounds and their methods of use
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United States of America Patent
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Aug 22, 2017
Grant Date -
Jul 7, 2016
app pub date -
Aug 1, 2014
filing date -
Aug 2, 2013
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Abstract
Provided are isocitrate dehydrogenase 2 (IDH2) inhibitor compounds useful for treating cancer and methods of treating cancer, comprising administering to a subject in need thereof a compound described herein. Also provided are polymorphic forms of the IDH2 inhibitor compounds characterized by X Ray powder diffraction patterns, having improved physicochemical properties that influence in vivo dissolution rate for formulation purposes.
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