Prophylactic and/or therapeutic agent for mild cognitive impairment

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United States of America Patent

PATENT NO 9737524
SERIAL NO

14860057

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided is a prophylactic and/or therapeutic drug for mild cognitive impairment, which can improve interstitial flow in cerebral blood vessel and the like to achieve sufficient clearance of harmful proteins accumulated in the brain. The prophylactic and/or therapeutic drug includes 6-[4-(1-cyclohexyl-1H-tetrazole-5-yl)butoxy]3,4-dihydrocarbostyril or a salt thereof as an active ingredient. The prophylactic and/or therapeutic drug can improve a flow of interstitial fluid around blood vessels in a drainage pathway to excrete harmful proteins. The prophylactic and/or therapeutic drug for mild cognitive impairment may take the form of a pharmaceutical product for oral administration, a liquid pharmaceutical product for oral administration, or an injectable preparation. The prophylactic and/or therapeutic drug for mild cognitive impairment can be used for the prevention and/or treatment of cerebral amyloid angiopathy, and can also be used for improvement of Lewy body disease, Down's syndrome, or macular degeneration.

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Patent Owner(s)

Patent OwnerAddress
FOUNDATION FOR BIOMEDICAL RESEARCH AND INNOVATION AT KOBE6-3-7 MINATOJIMA MINAMIMACHI CHUO-KU KOBE-SHI HYOGO 6500047 ?6500047

International Classification(s)

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  • 2015 Application Filing Year
  • A61K Class
  • 16157 Applications Filed
  • 11882 Patents Issued To-Date
  • 73.55 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ihara, Masafumi Hyogo, JP 14 4
Maki, Takakuni Hyogo, JP 4 4
Taguchi, Akihiko Hyogo, JP 14 10

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Patent Citation Ranking

  • 2 Citation Count
  • A61K Class
  • 45.09 % this patent is cited more than
  • 8 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges763281956782001332911183139501 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +050010001500200025003000350040004500500055006000650070007500800085009000

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