Optical capture and isolation of circulating tumor cells in a micro-fluidic device utilizing size selective trapping with optical cogwheel tweezers
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United States of America Patent
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Aug 15, 2017
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Apr 9, 2015
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Apr 9, 2015
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Embodiments generally relate to devices, systems and methods for separating CTCs from blood cells using optical trapping, such as use of optical cogwheel tweezers. Through a pre-filtration process, using optical cogwheel tweezers, desired cells from a cell sample can be filtered from a relatively dilute sample. The filtered sample can then be analyzed by more precise means to determine overall concentrations from the original sample while maintaining cell viability.
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