Segmented micro RNA mimetics

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United States of America Patent

PATENT NO 9732342
SERIAL NO

14747264

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Abstract

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This invention relates generally to segmented oligonucleotides capable of modulating gene expression. Specifically, the instant invention relates to segmented microRNA (miRNA) oligonucleotides, including segmented miRNA precursors and segmented pre-microRNAs. The invention also relates to compositions comprising such segmented oligonucleotides, as well as to methods of making and using such oligonucleotides for diagnosis and treatment of diseases associated or causally linked to aberrant levels or activities of gene expression, including aberrant levels of coding and/or non-coding RNA.

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Patent Owner(s)

Patent OwnerAddress
SIRNA THERAPEUTICS INC300 THIRD STREET CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chorn, Guillaume San Francisco, US 6 74
Lim, Lee San Francisco, US 12 109
Zhao, Lihong Walnut Creek, US 26 100

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