WNT7A compositions and method of using the same

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United States of America Patent

PATENT NO 9732130
SERIAL NO

14344309

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Abstract

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There are provided compositions and methods for modulating stem cell division, in particular, division symmetry. It has been demonstrated that Wnt7a polypeptide fragments promoting symmetrical expansion of stem cells. The compositions and methods of the invention are useful, for example, in modulating stem cell division symmetry in vitro, ex vivo, and in vivo, in replenishing and expanding the stem cell pool, and in promoting the formation, maintenance, repair and regeneration of tissue.

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Patent Owner(s)

Patent OwnerAddress
OTTAWA HOSPITAL RESEARCH INSTITUTEOTTAWA ON K1N 6N5

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bentzinger, Conrad Florian Ottawa, CA 3 6
Rudnicki, Michael A Ottawa, CA 19 148
Zinoviev, Radoslav New Haven, US 1 6

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