Protein retrosplicing enabled by a double ligation reaction
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Aug 15, 2017
Issued Date -
N/A
app pub date -
May 21, 2013
filing date -
May 21, 2012
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
Proteins containing a C-terminal thioester are important intermediates in semi-synthesis. Currently there is one main method for the synthesis of protein thioesters that relies upon the use of engineered inteins. The invention involves, in some aspects a method, utilizing Sortase A, for preparation of recombinant proteins containing a C-terminal αthioester. This new method for double ligatation is useful for synthesizing new or naturally occurring molecules such as a protein thioester.
First Claim
Family
International Classification(s)
- [Classification Symbol]
- [Patents Count]
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully