Vaccine formulations comprising saponin-containing adjuvants
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United States of America Patent
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Aug 15, 2017
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Jul 16, 2015
app pub date -
Feb 26, 2015
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Sep 10, 2009
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Abstract
The present invention provides for a novel oil-in-water (O/W) emulsion, with increased stability in the presence of bacterial or viral suspensions, especially those concentrated and non-purified (crude extracts) or minimally purified. The emulsion of the present invention can act as vehicle for the delivery of a pharmaceutical composition comprising at least one immunogen and, in particular, an immunogen selected from the group consisting of an inactivated pathogen, an attenuated pathogen, a subunit, a recombinant expression vector, and a plasmid or combinations thereof.
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