Bruton's tyrosine kinase inhibitor combinations and uses thereof

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United States of America Patent

PATENT NO 9730938
SERIAL NO

14820434

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Abstract

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Disclosed herein are methods, compositions, and kits for treating a B-cell malignancy comprising administering a combination of a BTK inhibitor (e.g. ibrutinib) and a PIM inhibitor. Also disclosed herein are methods, compositions, and kits for treating a BTK-resistant B-cell malignancy comprising administering a combination of a BTK inhibitor (e.g. ibrutinib) and a PIM inhibitor.

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Patent Owner(s)

Patent OwnerAddress
PHARMACYCLICS LLC995 EAST ARQUES AVENUE SUNNYVALE CA 94085

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Balasubramanian, Sriram North Wales, US 71 459
Chang, Betty Cupertino, US 11 340
Cheung, Leo Fremont, US 18 1754
Hsieh, Hsin-Kang San Jose, US 3 41
Kuo, Hsu-Ping Sunnyvale, US 7 109
Xue, Ling Beijing, CN 4 32

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