Methods and compositions for the diagnosis and prognosis of Alzheimer's disease
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United States of America Patent
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Aug 8, 2017
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app pub date -
Apr 15, 2010
filing date -
Apr 15, 2009
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Abstract
The invention relates to methods of diagnosing Alzheimer's disease (AD) in a subject and methods of determining the prognosis in patients with AD. The adhesion molecules P-selectin and L-selectin are described for the first time for use as biomarkers to aid in the diagnosis of AD. The invention further describes the use of one or more of L-selectin, MCP-1, IL-1α, IL-8 and IFN-γ to aid in the prognosis of either accelerated cognitive decline (ACD) or slow cognitive decline (SCD) in patients with AD.
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