Non-ionic, low osmolar contrast agents for delivery of antisense oligonucleotides and treatment of disease

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United States of America Patent

PATENT NO 9725716
SERIAL NO

14363670

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Abstract

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Disclosed are compositions comprising an antisense oligonucleotide and a non-ionic, low-osmolar contrast agent. Also disclosed are methods of delivering an antisense oligonucleotide to a target sire comprising incorporating the antisense oligonucleotide into a composition comprising a non-ionic, low-osmolar contrast agent. Also disclosed are methods of treating a neurodegenerative disease comprising administering one or more of the compositions disclosed herein.

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Patent Owner(s)

  • OHIO STATE INNOVATION FOUNDATION;RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL;OHIO STATE INNOVATION FOUNDATION AND RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burghes, Arthur Columbus, US 16 103
Kaspar, Brian New Albany, US 15 433
Porensky, Paul Worthington, US 13 101

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