Pulmonary administration of immunoglobulin single variable domains and constructs thereof

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United States of America Patent

PATENT NO 9725522
SERIAL NO

15063961

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Abstract

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In one aspect, the invention relates to a method suitable for administering protein therapeutic molecules orally, sublingually, topically, intravenously, subcutaneously, nasally, vaginally, rectally or by inhalation so as to avoid inactivation, by using VHH polypeptides derived from Camelidae antibodies. The invention further relates to the said therapeutic molecules. The invention further a method for delivering therapeutic molecules to the interior of cells. The invention further relates to anti-IgE therapeutic molecules.

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Patent Owner(s)

  • ABLYNX N.V.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bouche, Marie-Paule Lucienne Armanda Gentbrugge, BE 16 137
De, Buck Stefan Buesserach, CH 12 64
De, Haard Hans Oudelande, NL 49 292
Depla, Erik Destelbergen, BE 85 478
Sablon, Erwin Merchtem, BE 18 161
Saelens, Xavier Leper, BE 17 116
Schepens, Bert Drongen, BE 13 93
Silence, Karen Overijse, BE 53 754
Vaeck, Mark Hofstade, BE 16 213
Van, Bergen En Henegouwen Paul M P Utrecht, NL 9 136
Vanlandschoot, Peter Bellem, BE 28 303

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