Tumor necrosis factor receptor soluble factor binding (TNFRSF-binding) agents

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United States of America Patent

PATENT NO 9724390
SERIAL NO

15014134

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Abstract

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Polypeptides and agents that bind a TNF receptor superfamily protein are disclosed, particularly agents that specifically bind GITR, OX40, or CD40. The polypeptides or agents may include fusion polypeptides, particularly polypeptides comprising GITRL, OX40L, or CD40L and/or bispecific agents. Also disclosed are methods of using the polypeptides or agents for inducing and/or enhancing the immune response, as well as methods for the treatment of diseases such as cancer.

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Patent Owner(s)

Patent OwnerAddress
ONCOMED PHARMACEUTICALS INC800 CHESAPEAKE DRIVE REDWOOD CITY CA 94063-4748

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gurney, Austin L San Francisco, US 2150 10194

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