Unextracted tooth root canal filler and dental tissue regeneration method for unextracted tooth

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9724368
APP PUB NO 20140099605A1
SERIAL NO

14102295

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed is a root canal filler for non-extracted tooth which causes no internal resorption or external resorption in a tooth with complete root formation, shows no odontoclast, and contributes to the regeneration of a dental tissue in which odontoblasts are smoothly aligned on the dentin wall. After pulpectomy or enlargement/cleaning of an infected root canal, a root canal filler for non-extracted tooth, which comprises tooth pulp stem cells and an extracellular matrix, is inserted into the apical side of the root canal of the non-extracted tooth. The tooth pulp stem cells may be, for example, dental pulp CXCR4-positive cells. It is preferred to attach, to the crown side of the root canal, migration factor(s) including at least one factor selected from among a cell migration factor, a cell proliferation factor, a neurotrophic factor and an angiogenic factor.

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Patent Owner(s)

Patent OwnerAddress
AIR WATER INCSAPPORO-SHI HOKKAIDO 060-0003

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Iohara, Koichiro Obu, JP 11 101
Nakashima, Misako Obu, JP 20 136

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