Use of maleimide derivatives for preventing and treating leukemia

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United States of America Patent

PATENT NO 9724331
SERIAL NO

14650939

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Abstract

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The present invention is related to a compound of formula (I): a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use in a method for the treatment and/or prevention of leukemia, wherein X is selected from the group consisting of N—R1, O and S; R1 is selected from the group consisting of alkyl, cycloalkyl, aryl, arylalkyl and hydrogen; R2 is selected from the group consisting of indolyl, substituted indolyl, azaindolyl and substituted azaindolyl; and R3 is selected from the group consisting of aryl, substituted aryl, unsubstituted heteroaryl, heterocyclyl and substituted heterocyclyl.

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Patent Owner(s)

Patent OwnerAddress
CENTOGENE GMBHAM STRANDE 7 ROSTOCK 18055

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beller, Matthias Nienhagen, DE 163 664
Eisenloeffel, Christian Rostock, DE 1 0
Frech, Moritz Neu Broderstorf, DE 3 0
Junghanss, Christian Rostock, DE 3 0
Lukas, Jan Rostock, DE 28 430
Pews-Davtyan, Anahit Rostock, DE 5 15
Rolfs, Arndt Berlin, DE 19 32

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