Protein with recombinase activity for site-specific DNA-recombination
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United States of America Patent
Stats
-
Aug 1, 2017
Issued Date -
N/A
app pub date -
Jul 21, 2016
filing date -
Jul 24, 2012
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
The invention relates to the use of a protein with recombinase activity to catalyze a site-specific DNA recombination and a method for producing a site-specific DNA recombination. The invention is applicable alone or in combination with other recombinase systems for genetic manipulation, for example in medical research. The objective of the invention is solved by the use of a protein with recombinase activity to catalyze a site-specific DNA recombination at, preferably at two, recognition sites that are identical or reverse complementary to each other. The invention also includes a method for producing a site-specific DNA recombination comprising the steps of a) providing a cell comprising at least two recognition sites that are identical or reverse complementary to each other; and b) contacting a protein with recombinase activity with the recognition sites, thereby producing the site-specific DNA-recombination.
First Claim
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International Classification(s)
- 2016 Application Filing Year
- C07H Class
- 1039 Applications Filed
- 891 Patents Issued To-Date
- 85.76 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 1 Citation Count
- C07H Class
- 56.20 % this patent is cited more than
- 8 Age
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