Monoclonal antibodies with enhanced ADCC function

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United States of America Patent

PATENT NO 9718889
SERIAL NO

14617836

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Abstract

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The invention concerns a method for obtaining and selecting monoclonal antibodies by an ADCC-type test, said antibodies capable of activating type III Fcy receptors and having a particular glycan structure. The inventive anti-D antibodies can be used for preventing Rhesus isoimmunisation in Rh negative persons, in particular for haemolytic disease in a new-born baby or for uses such as idiopathic thrombocytopenic purpura (ITP).

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Patent Owner(s)

Patent OwnerAddress
LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIESLES ULIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beliard, Roland Santes, FR 14 168
Bihoreau, Nicolas Orsay, FR 32 250
Bourel, Dominique La Madeleine, FR 29 306
Glacet, Amaud Gondecourt, FR 4 6
Nony, Emmanuel Antony, FR 36 246
Romeuf, Christophe De Lille, FR 9 38

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