Plasminogen activator inhibitor-1 inhibitors and methods of use thereof

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United States of America Patent

PATENT NO 9718760
SERIAL NO

14439843

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or disorder associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to prevent or reduce thrombosis and fibrosis, to promote thrombolysis, and to modulate lipid metabolism and treat diseases or disorders associated with elevated PAI-1, cholesterol, or lipid levels.

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Patent Owner(s)

Patent OwnerAddress
THE REGENTS OF THE UNIVERSITY OF MICHIGAN1600 HURON PARKWAY 2ND FLOOR OFFICE OF TECHNOLOGY TRANSFER ANN ARBOR MI 48109-2590

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abernathy, Gregory Dublin, US 2 3
Emal, Cory Ann Arbor, US 8 28
Lawrence, Daniel A Ann Arbor, US 26 86
Li, Shih-Hon Ypsilanti, US 10 37
Reinke, Ashley Ann Arbor, US 4 3
Warnock, Mark Brighton, US 6 28

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  • 1 Citation Count
  • C07D Class
  • 42.14 % this patent is cited more than
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges158718941835528419501 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7081 - 90010020030040050060070080090010001100120013001400150016001700180019002000

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