Method for detecting genes sensitive to low-level ionizing radiation

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United States of America Patent

PATENT NO 9714453
APP PUB NO 20170058358A1
SERIAL NO

15346680

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Abstract

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A method for detecting genes sensitive to low-level ionizing radiation and genes detected by the method. More specifically, genes sensitive to low-level ionizing radiation, discovered in a carcinogenic entity and verified in a normal entity are detected by subjecting a cancerous AKR/J mouse and a normal ICR mouse to low-level radiation. Thymus is collected therefrom, and glycometabolism-related genes are classified via microarray processing of the thymus. The genes are amplified and the levels of gene expression are measured. Thus, a gene having a specific reaction to radiation can be accurately detected by preventing the interference of confounding variables.

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Patent Owner(s)

Patent OwnerAddress
KOREA HYDRO & NUCLEAR POWER CO LTD1655 BULGUK-RO YANGBUK-MYEON GYEONGJU-SI GYEONGSANGBUK-DO 38120

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bong, Jin Jong Seoul, KR 14 1
Choi, Moo Hyun Seoul, KR 14 0
Choi, Seung Jin Seoul, KR 41 113
Kim, Hee Sun Uijeongbu, KR 33 155
Shin, Seok Cheol Seoul, KR 14 1

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