PEGylated tyrosyl-tRNA synthetase polypeptides

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United States of America Patent

PATENT NO 9714419
SERIAL NO

14237544

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Abstract

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The present invention provides PEGylated tyrosyl-tRNA synthetase (YRS) polypeptides, compositions comprising the same, and methods of using such polypeptides and compositions for treating or diagnosing a variety of conditions. The PEGylated YRS polypeptides of the invention have improved controlled release properties, stability, half-life, and other pharmacokinetic properties compared to non-PEGylated YRS polypeptides.

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Patent Owner(s)

Patent OwnerAddress
ATYR PHARMA INC3545 JOHN HOPKINS COURT SUITE #250 SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Buechler, Ying Ji Carlsbad, US 4 64
Do, Minh-Ha San Diego, US 7 104
Mendlein, John D Encinitas, US 118 2854
Vasserot, Alain P Carlsbad, US 71 565
Watkins, Jeffrey D Encinitas, US 12 380
Wu, Chi-Fang San Diego, US 14 168

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