Method for producing 2-amino-6-methylnicotinic acid
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United States of America Patent
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Jul 25, 2017
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May 11, 2017
app pub date -
Jun 27, 2014
filing date -
Jun 27, 2014
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Abstract
The present invention provides a method for producing 2-amino-6-methylnicotinic acid represented by formula [I], wherein the production method comprises: (a) reacting 2-chloro-3-cyano-6-methylpyridine represented by formula [II] in an ammonia aqueous solution to obtain a reaction solution containing 2-amino-6-methylnicotinamide represented by formula [III]; and (b) removing the ammonia from the reaction solution, then reacting the 2-amino-6-methylnicotinamide represented by formula [III]with a base to produce 2-amino-6-methylnicotinic acid represented by formula [I].
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