Methods for producing a population of pancreatic beta-cells

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United States of America Patent

PATENT NO 9708608
APP PUB NO 20150240235A1
SERIAL NO

14431857

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Abstract

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The present invention relates to an in vitro or ex vivo method for producing a population of pancreatic beta-cells, comprising the step of inhibiting the expression or the activity of Arx in a population of pancreatic alpha-cells. The present invention also relates to method for inducing the conversion of pancreatic alpha-cells in pancreatic beta-cells in a patient in need thereof.

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Patent Owner(s)

Patent OwnerAddress
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)PARIS FRA
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)101 RUE DE TOLBIAC PARIS CEDEX 13 75654
UNIVERSITE NICE SOPHIA ANTIPOLIS28 AVENUE VALROSE NICE F-06103

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Al-Hasani, Keith Nice, FR 2 5
Ben-Ohtman, Nouha Nice, FR 1 2
Collombat, Patrick Nice, FR 8 3
Courtney, Monica Nice, FR 1 2
Gjernes, Elisabet Nice, FR 1 2
Mansouri, Ahmed Goettingen, DE 3 2

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