Monoclonal antibodies with enhanced ADCC function

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United States of America Patent

PATENT NO 9708409
SERIAL NO

14157061

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Abstract

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The invention concerns a method for obtaining and selecting monoclonal antibodies by an ADDC-type test, said antibodies capable of activating type III Fcy receptors and having a particular glycan structure. The inventive anti-D antibodies can be used for preventing Rhesus isoimmunisation in Rh negative persons, in particular for haemolytic disease in a new-born baby of for uses such as idiopathic thrombocytopenic pupura 9ITP).

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Patent Owner(s)

Patent OwnerAddress
LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIESLES ULIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beliard, Roland Gif sur Yvette, FR 14 168
Bihoreau, Nicolas Orsay, FR 32 250
Bourel, Dominique La Madeleine, FR 29 306
De, Romeuf Christophe Lille, FR 42 230
Glacet, Arnaud Gondecourt, FR 27 217
Nony, Emmanuel Antony, FR 36 246

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