4′-azido, 3′-fluoro substituted nucleoside derivatives as inhibitors of HCV RNA replication
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United States of America Patent
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Jul 18, 2017
Grant Date -
Dec 18, 2014
app pub date -
Dec 17, 2012
filing date -
Dec 20, 2011
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Abstract
The present invention relates to the use of 3′-fluoro, 4′-azido nucleoside phosphoramidate prodrug derivatives of formula I
First Claim
all claims..Other Claims data not available
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Country | kind | publication No. | Filing Date | Type | Sub-Type |
---|---|---|---|---|---|
KR | B1 | KR101687084 | Dec 17, 2012 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
PATENT SPECIFICATION | HCV RNA 복제의 억제제로서 4'-아지도, 3'-플루오로 치환된 뉴클레오시드 유도체 | Dec 15, 2016 | |||
CA | C | CA2869317 | Dec 17, 2012 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
PATENT (SECOND LEVEL) | 4'-AZIDO,3'-FLUORO SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION | May 17, 2016 | |||
EA | B1 | EA024847 | Dec 17, 2012 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
PATENT | 4'-АЗИДО,3'-ФТОРЗАМЕЩЕННЫЕ ПРОИЗВОДНЫЕ НУКЛЕОЗИДОВ В КАЧЕСТВЕ ИНГИБИТОРОВ РЕПЛИКАЦИИ РНК ВИРУСА ГЕПАТИТА С | Oct 31, 2016 | |||
SG | A | SG11201403086Y | Dec 17, 2012 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
UK PATENTS REGISTERED | 4'-AZIDO, 3'-FLUORO SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION | Jul 30, 2014 | |||
AU | B2 | AU2012357986 | Dec 17, 2012 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
PATENT PROCEEDED BY OPI | 4'-Azido, 3'-fluoro substituted nucleoside derivatives as inhibitors of HCV RNA replication | Feb 02, 2017 | |||
JP | B2 | JP6118336 | Dec 17, 2012 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
PUBLISHED GRANTED PATENT (SECOND LEVEL) | HCVのRNA複製の阻害剤としての4’−アジド、3’−フルオロ置換されたヌクレオシド誘導体 | Apr 19, 2017 | |||
NZ | A | NZ625844 | Dec 17, 2012 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
PATENT APPLICATION | 4’-azido, 3’-fluoro substituted nucleoside derivatives as inhibitors of hcv rna replication | Aug 26, 2016 | |||
MX | B | MX350810 | Dec 17, 2012 | Not Available | Grant |
Type : Not Available Sub-Type : Grant | |||||
GRANTED PATENT/ GRANTED UTILITY MODEL | DERIVADOS DE LOS NUCLEOSIDOS SUSTITUIDOS EN 4 '-AZIDO, 3 '-FLUORO COMO INHIBIDORES DE LA REPLICACION DEL RNA DEL VHC. | Sep 20, 2017 | |||
BR | A2 | BR112014015066 | Dec 17, 2012 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
APPLICATION FOR A PATENT OF INVENTION / PIPELINE PATENT PUBLISHED WITHOUT SEARCH REPORT | derivados de nucleosídeos 4'azido-3'-flúor substituídos como inibidores de replicação do rna de hcv | Jun 13, 2017 | |||
EP | B1 | EP2794628 | Dec 17, 2012 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
Patent | 4'-AZIDO-3'-FLUORO SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION | Mar 29, 2017 | |||
CN | A | CN104011060 | Dec 17, 2012 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
UNEXAMINED APPLICATION FOR A PATENT FOR INV. | 4'-azido,3'-fluoro substituted nucleoside derivatives as inhibitors of HCV RNA replication | Aug 27, 2014 | |||
CN | A | CN108409820 | Dec 17, 2012 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
UNEXAMINED APPLICATION FOR A PATENT FOR INV. | As 4 '-azidos of HCV rna replicon inhibitor, 3 '-fluorine-substituted nucleoside derivates | Aug 17, 2018 | |||
WO | A1 | WO2013092447 | Dec 17, 2012 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
INTERNATIONAL APPLICATION PUBLISHED WITH INTERNATIONAL SEARCH REPORT | 4'-AZIDO, 3'-FLUORO SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION | Jun 27, 2013 | |||
PE | A1 | PE20141599 | Dec 17, 2012 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
PATENT APPLICATION | DERIVADOS DE LOS NUCLEOSIDOS SUSTITUIDOS EN 4'-AZIDO, 3'-FLUORO COMO INHIBIDORES DE LA REPLICACION DEL RNA DEL VHC | Oct 30, 2014 | |||
UA | C2 | UA110428 | Dec 17, 2012 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
PATENT GRANT. UPON THE USSR APPLICATION,FOR WHICH NO POS. DEC. MADE NATIONAL APPLICATION | 4'-АЗИДО, 3'-ФТОРЗАМІЩЕНІ ПОХІДНІ НУКЛЕОЗИДІВ ЯК ІНГІБІТОРИ РЕПЛІКАЦІЇ РНК ВІРУСУ ГЕПАТИТУ C | Dec 25, 2015 | |||
CR | A | CR20140255 | May 28, 2014 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
PATENT APPLICATION | DERIVADOS DE LOS NUCLEÓSIDOS SUSTITUIDOS EN 4'-AZIDO, 3'-FLUORO COMO INHIBIDORES DE LA REPLICACIÓN DEL RNA DEL VHC | Aug 20, 2014 | |||
PH | A1 | PH12014501283 | Jun 06, 2014 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
Patent Application | 4`-AZIDO, 3``-FLUORO SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION | Sep 08, 2014 | |||
IN | A | IN2014CN04530 | Jun 17, 2014 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
PATENT OR PATENT OF ADDITION | 4 azido 3 fluoro substituted nucleoside derivatives as inhibitors of hcv rna replication | Sep 11, 2015 | |||
CL | A1 | CL2014001599 | Jun 18, 2014 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
PATENT APPLICATION | Compuestos derivados de nucleosidos sustituidos en 4’-azido, 3’-fluoro o sus sales, como inhibidores de la replicacion del rna del vhc; composicion farmaceutica que los comprende; y su uso para el tratamiento o la profilaxis de la infeccion por el virus de la hepatitis c (vhc). | Nov 03, 2014 | |||
CO | A2 | CO6990719 | Jun 20, 2014 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
APPLICATION DERIVED FROM A PCT APPLICATION | Derivados de los nucleósidos sustituidos en 4´-azido, 3´-fluoro como inhibidores de la replicación del rna del vhc | Jul 10, 2014 | |||
MA | B1 | MA35749 | Jun 25, 2014 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
GRANTED PATENT | Dérivés nucléosidiques 4'-azido, 3'-fluoro substitués en tant qu'inhibiteurs de la réplication de l'arn du vhc | Dec 01, 2014 |
- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
RIBOSCIENCE LLC | 3901 LAGUNA AVENUE PALO ALTO CA 94306 |
International Classification(s)
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Smith, Mark | San Francisco, US | 353 | 5522 |
# of filed Patents : 353 Total Citations : 5522 | |||
Talamas, Francisco Xavier | Livingston, US | 43 | 341 |
# of filed Patents : 43 Total Citations : 341 | |||
Zhang, Jing | Parsippany, US | 966 | 8974 |
# of filed Patents : 966 Total Citations : 8974 | |||
Zhang, Zhuming | Hillsborough, US | 58 | 543 |
# of filed Patents : 58 Total Citations : 543 |
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Full Text
US Patent Application No: 2017/0299,503
LASER DETECTION SYSTEM AND METHOD
Abstract
A laser detection system comprises a plurality of lasers wherein each laser is configured to produce a respective laser beam for excitation of one or more different compounds, a sample cell for containing a volume of sample gas, at least one directing device configured to direct the laser beams to the sample cell, wherein the at least one directing device is configured to direct the laser beams along a common optical path to the sample cell, and a detector apparatus for detecting light output from the cell.
Description
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